Radiation Necrosis: Diagnostic Considerations and Treatment Strategies

Commercial Supporter 

Baptist Health gratefully acknowledges the commercial support provided by Elekta for this activity.

Target Audience

Neurosurgeons, medical physicists, radiation oncologists and neuro-otolaryngologists.

Learning Objectives

  • Describe the epidemiology and etiology of radiation injury and necrosis. 
  • Identify radiation necrosis imaging findings and risk factors.
  • Assess the evidence for medical and surgical options for radiation necrosis management. 
Additional information
Bibliography: 
  • Turnquist, C., Harris, B. T., & Harris, C. C. (2020). Radiation-induced brain injury: current concepts and therapeutic strategies targeting neuroinflammation. Neuro-oncology advances, 2(1), vdaa057.
  • Miller, J. A., Bennett, E. E., Xiao, R., Kotecha, R., Chao, S. T., Vogelbaum, M. A., ... & Mohammadi, A. M. (2016). Association between radiation necrosis and tumor biology after stereotactic radiosurgery for brain metastasis. International Journal of Radiation Oncology* Biology* Physics, 96(5), 1060-1069.
  • Furuse, M., Nonoguchi, N., Kuroiwa, T., Miyamoto, S., Arakawa, Y., Shinoda, J., ... & Miyatake, S. I. (2016). A prospective, multicentre, single-arm clinical trial of bevacizumab for patients with surgically untreatable, symptomatic brain radiation necrosis. Neuro-Oncology Practice, 3(4), 272-280.
Course Summary
Available credit: 
  • 1.00 AMA PRA Category 1 Credit™
  • 1.00 General certificate of attendance
  • 1.00 Nurse Practitioners
Course opens: 
05/01/2023
Course expires: 
01/31/2024
Part of: 
Miami Cancer Institute & Miami Neuroscience Institute: Miami Radiosurgery e-Learning Series

Yazmin Odia, M.D., M.S., FAAN
Chief of Neuro-Oncology
Miami Cancer Institute
Miami Neuroscience Institute

Yazmin Odia, M.D., faculty for this educational activity, provides trial support for Chimerix, Bristol-Myers Squibb and MimiVax; is on the independent data monitoring board for Actuate, the data safety and monitoring board for GammaTile and the advisory board for Novocure; and is a consultant for Istari Oncology and PharPoint Research. She has indicated that the presentation or discussion will not include off-label or unapproved product usage.

Rupesh Kotecha, M.D., conference director of this educational event, has received honorariums from Elekta AB, Accuray, ViewRay, Novocure and Elsevier, and research support from Medtronic, Blue Earth Diagnostics, Novocure, Exelixis, CT Medical, AstraZeneca and ViewRay. He is also a member of the speakers’ bureau with Novocure.

Michael W. McDermott, M.D., conference director of this educational event, is a consultant with Deinde Medical and Stryker.

All of the relevant financial relationships listed for these individuals have been mitigated.

Non-faculty contributors and others involved in the planning, development and editing/review of the content have no relevant financial relationships to disclose with ineligible companies*.  

*Ineligible companies – Companies whose primary business is producing, marketing, selling, re-selling or distributing healthcare products used by or on patients.

Disclosure Policy and Disclaimer

Baptist Health South Florida is accredited by the Accreditation Council for Continuing Medical Education (ACCME) to provide continuing medical education for physicians. Baptist Health has been re-surveyed by the ACCME and awarded Commendation for 6 years as a provider of CME for physicians.
              
Baptist Health South Florida designates this enduring material for a maximum of 1 AMA PRA Category 1 Credits™. Physicians should claim only the credit commensurate with the extent of their participation in the activity.

Available Credit

  • 1.00 AMA PRA Category 1 Credit™
  • 1.00 General certificate of attendance
  • 1.00 Nurse Practitioners
Please login or register for a Baptist Health CME account to take this course.

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