MCI Multispecialty Grand Rounds –Personalizing Treatment of Metastatic Hormone-Sensitive Prostate Cancer

February 9, 2026

Management of metastatic hormone-sensitive prostate cancer (mHSPC) has undergone substantial advances over the past five years and continues to evolve. Beyond intensified androgen receptor pathway inhibition, emerging therapeutic strategies targeting the homologous recombination repair (HRR) pathway, the AKT signaling axis, and prostate-specific membrane antigen
(PSMA) have demonstrated meaningful clinical efficacy. Importantly, a subset of patients achieving robust and durable responses may be appropriate candidates for treatment de-escalation, with the goal of optimizing quality of life while mitigating long-term toxicity. This presentation will provide a comprehensive review of the latest clinical data within this framework.

Target Audience

Oncologists, Radiation Oncologists, Hematology Oncologists, Radiation Therapists, Endocrinologists, Pulmonologists, Otolaryngologists, Urologists, Colo -rectal Surgeons, Neurologists, General Surgeons, General Practitioners, Obstetricians and Gynecologists, Nurses, Pharmacists, Patient Navigators and all other interested healthcare professionals.

Learning Objectives

  • Demonstrate an evidence-based understanding of the clinical effectiveness of intensified androgen receptor pathway blockade, PARP inhibitors, and other emerging targeted therapies in the management of metastatic hormone-sensitive prostate cancer (mHSPC).
  • Identify and appraise the spectrum of adverse effects associated with these therapeutic approaches and apply strategies to mitigate toxicity while maintaining treatment efficacy.
  • Assess and interpret relevant molecular and clinical biomarkers to guide individualized treatment selection, optimize patient outcomes, and advance precision oncology in mHSPC.
Course Summary
Available credit: 
  • 1.00 AMA PRA Category 1 Credit™
  • 1.00 General certificate of attendance
  • 1.00 Florida Board of Dietitians
  • 1.00 Florida Board of Laboratory Personnel
  • 1.00 Nurse Practitioners
  • 1.00 Florida Board of Nursing
  • 1.00 Florida Board of Pharmacy
  • 1.00 Florida Board of Respiratory Therapy
Course opens: 
12/14/2025
Course expires: 
04/30/2026
Event starts: 
02/09/2026 - 7:30am EST
Event ends: 
02/09/2026 - 8:30am EST
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Live Webinar
United States

Neeraj Agarwal, M.D.
Medical Oncologist
Huntsman Cancer Institute
University of Utah
Salt Lake City, Utah

Neeraj Agarwal M.D., faculty for this educational activity, has no relevant financial relationships with ineligible companies* to disclose, and has indicated that the presentation or discussion will
not include off-label or unapproved product usage.

Firas El Chaer, M.D., conference director of this educational activity, is a consultant for Morphosys and an advisor for Amgen, PharmaEssentia, Geron, Syndax, Abbvie, AMPO and CTI Biopharma.  

Robert Press, M.D., conference director of this educational activity, does not have any financial relationships with ineligible companies to disclose.

All relevant financial relationships listed for these individuals have been mitigated. 

Non-faculty contributors and others involved in the planning, development and editing/review of the content have no relevant financial relationships with ineligible companies* to disclose.  

*Ineligible Companies – Companies whose primary business is producing, marketing, selling, re-selling or distributing healthcare products used by or on patients.

Disclosure Policy and Disclaimer

Baptist Health South Florida is accredited by the Accreditation Council for Continuing Medical Education (ACCME) to provide continuing medical education for physicians. Baptist Health has been re-surveyed by the ACCME and awarded Commendation for 6 years as a provider of CME for physicians.

Baptist Health South Florida designates this live activity for a maximum of 1 AMA PRA Category 1 Credit™. Physicians should claim only the credit commensurate with the extent of their participation in the activity.

This activity has been approved for 1 credit hour, CE Broker Course #20-1264966, by the Florida Boards of Medicine, Osteopathic Medicine and by the Florida Council of Physician Assistants.

This activity has also been approved for 1 credit hour for Nurse Practitioners, Nurses, Laboratory Personnel, Pharmacists and Techs, Dietitians, Respiratory Therapists. Baptist Health South Florida CE Broker Provider #50-182.

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American Board of Surgery - Maintenance of Certification (MOC) - Accredited CME- Complex General Surgery Oncology

Successful completion of this CME activity, which includes participation in the evaluation component, enables the learner to earn credit toward the CME of the American Board of Surgery’s Continuous Certification program. It is the CME activity provider's responsibility to submit learner completion information to ACCME for the purpose of granting ABS credit.

Your participation information will be shared with specialty boards through the ACCME's PARS reporting system. Submissions are recorded in approximately 48 hours. You will receive an email when your credits have been processed.

Available Credit

  • 1.00 AMA PRA Category 1 Credit™
  • 1.00 General certificate of attendance
  • 1.00 Florida Board of Dietitians
  • 1.00 Florida Board of Laboratory Personnel
  • 1.00 Nurse Practitioners
  • 1.00 Florida Board of Nursing
  • 1.00 Florida Board of Pharmacy
  • 1.00 Florida Board of Respiratory Therapy
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