Antimicrobial Stewardship Program: Clostridioides difficile (C. difficile) Testing and Management

Clostridioides difficile is the most commonly recognized cause of infectious diarrhea in the healthcare setting. In this course, Jorge Murillo, M.D. and Alice Margulis Landayan, Pharm.D. discuss inpatient testing and clinical management via clinical case discussions.

This course is the result of interdisciplinary educational planning and delivery by the Antimicrobial Stewardship Clinical Program and Continuing Education Subcommittee.

Commercial Supporter
Baptist Health gratefully acknowledges the commercial support provided by Cepheid.

Target Audience

Hospitalists, Infectious Disease Physicians, Critical Care Physicians, advanced practice registered nurses, physician assistants, physician associates, nurses, nurse practitioners, pharmacists, pharmacy technicians, respiratory therapists, laboratory personnel (microbiology) and all other interested healthcare providers.

Learning Objectives

  • Explain the prevalence, risk factors, and clinical manifestations of Clostridioides difficile infection (CDI) and distinguish clinical scenarios when C. difficile testing is advisable.
  • Implement a multimodal approach to CDI management.
Additional information
Bibliography: 
  • Kelly, C. R., Fischer, M., Allegretti, J. R., LaPlante, K., Stewart, D. B., Limketkai, B. N., & Stollman, N. H. (2021). ACG clinical guidelines: prevention, diagnosis, and treatment of Clostridioides difficile infections. Official journal of the American College of Gastroenterology| ACG, 116(6), 1124-1147.
  • Johnson, S., Lavergne, V., Skinner, A. M., Gonzales-Luna, A. J., Garey, K. W., Kelly, C. P., & Wilcox, M. H. (2021). Clinical practice guideline by the Infectious Diseases Society of America (IDSA) and Society for Healthcare Epidemiology of America (SHEA): 2021 focused update guidelines on management of Clostridioides difficile infection in adults. Clinical infectious diseases, 73(5), e1029-e1044.
  • Important Safety Alert Regarding Use of Fecal Microbiota for Transplantation. FDA. 2019-2022.
Course Summary
Available credit: 
  • 1.25 ABIM MOC II
  • 1.25 AMA PRA Category 1 Credit™
  • 1.25 General certificate of attendance
  • 1.20 Florida Board of Laboratory Personnel
  • 1.00 Nurse Practitioners
  • 1.00 Florida Board of Nursing
  • 1.25 Florida Board of Pharmacy
  • 1.00 Florida Board of Respiratory Therapy
Course opens: 
03/01/2024
Course expires: 
02/28/2027

Alice Margulis Landayan, Pharm. D., BCIDP
Antimicrobial Stewardship Clinical Pharmacy Specialist
South Miami Hospital
Miami, Florida 

Jorge Murillo, M.D., FIDSA, FACP
Infectious Diseases Physician
Baptist Health South Florida
Miami, Florida

Jorge Murillo, M.D., FIDSA, FACP, faculty for this educational activity, is on the speakers' bureau for Paratek Pharmaceuticals and his presentation will not include off-label or unapproved product usage in the presentation or discussion. All of the relevant financial relationships listed for this individual have been mitigated.

Alice Margulis Landayan, Pharm.D., BCIDP, faculty for this educational activity, indicated that she does not have relevant financial relationships with commercial interest companies, and she will not include off-label or unapproved product usage in the presentation or discussion.

Timothy P. Gauthier, Pharm. D., BCPS, BCIDP, faculty for this educational activity, is a consultant with Pattern Biosciences (formerly Klaris Diagnostics), GSK, Pfizer, First Line, Ferring, Gilead and Melinta. All of the relevant financial relationships listed for this individual have been mitigated.

Non-faculty contributors and others involved in the planning, development, and editing/review of the content have no relevant financial relationships to disclose with ineligible companies*

*Ineligible companies - Companies whose primary business is producing, marketing, selling, re-selling, or distributing healthcare products used by or on patients.

Baptist Health South Florida is accredited by the Accreditation Council for Continuing Medical Education (ACCME) to provide continuing medical education for physicians. Baptist Health has been re-surveyed by the ACCME and awarded Commendation for 6 years as a provider of CME for physicians.
              
Baptist Health South Florida designates this enduring material for a maximum of 1.25 AMA PRA Category 1 Credits™. Physicians should claim only the credit commensurate with the extent of their participation in the activity.

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American Board of Internal Medicine Maintenance of Certification

Successful completion of this CME activity, which includes participation in the evaluation component, enables the participant to earn up to 1.25 Medical Knowledge MOC point in the American Board of Internal Medicine's (ABIM) Maintenance of Certification (MOC) program. Participants will earn MOC points equivalent to the amount of CME credits claimed for the activity. It is the CME activity provider's responsibility to submit participant completion information to ACCME for the purpose of granting ABIM MOC credit.

Your participation information will be shared with specialty boards through the ACCME's PARS reporting system. Successful completion of a course examination is required. Submissions are recorded in approximately 48 hours. You will receive an email when your credits have been processed.

Through an agreement between the Accreditation Council for Continuing Medical Education and the Royal College of Physicians and Surgeons of Canada, medical practitioners participating in the Royal College MOC Program may record completion of accredited activities registered under the ACCME’s “CME in Support of MOC” program in Section 3 of the Royal College’s MOC Program.

Available Credit

  • 1.25 ABIM MOC II
  • 1.25 AMA PRA Category 1 Credit™
  • 1.25 General certificate of attendance
  • 1.20 Florida Board of Laboratory Personnel
  • 1.00 Nurse Practitioners
  • 1.00 Florida Board of Nursing
  • 1.25 Florida Board of Pharmacy
  • 1.00 Florida Board of Respiratory Therapy
Please login or register for a Baptist Health CME account to take this course.

Your participation information will be shared with specialty boards through the ACCME's PARS reporting system. Successful completion of a course examination is required. Submissions are recorded in approximately 48 hours. You will receive an email when your credits have been processed.

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