| Discuss dementia in the elderly. |
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| Present a case of rapidly progressive dementia (RPD) due to cortical Creutzfeldt–Jakob disease (CJD). |
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| Explain the diagnostic limitations of RT-QuIC testing in cortical CJD. |
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| Review the major types of CJD and prion propagation. |
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| Outline the clinical approach to diagnosis and management of RPD and prion diseases. |
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| Review the milestones of prion disease research |
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