The 11th Annual State of the Science Symposium brings together leading experts from our community to discuss the advancements, challenges, and future directions of critical care medicine. As we continue to face a rapidly changing healthcare environment, it is more important than ever to stay informed and updated on the latest evidence-based practices and standards of care for critically ill and injured patients. Critical care is a dynamic and evolving field, where even small changes in practice can have a significant impact on patient outcomes. This year’s symposium will emphasize the integration of the latest scientific evidence, technology, and patient-centered approaches into everyday clinical practice.