Optimizing Adoptive Cell Immunotherapeutics Via GPS

Robert Sackstein, M.D., discusses the next steps in immunotherapy and how improved delivery of vascularly administered, culture-expanded immune effector cells (e.g., CAR T-cells) can be achieved. 

Target Audience

Hematologists, oncologists, pathologists, radiation oncologists, oncology/hematology nurses, nurse practitioners, physician assistants, palliative care staff, pharmacists and other allied health care team members interested in the treatment of patients with hematologic malignancies.

Learning Objectives

  • Identify the molecular basis of cell migration. 
  • Illustrate how site-specific migration cells can be achieved for adoptive immunotherapy applications.
  • Explain how to execute improved site-specific cell trafficking, yielding higher efficacy, safer outcomes and lower costs for adoptive immunotherapy applications.

Supporters

The Continuing Medical Education Department gratefully acknowledges the following Corporate Philanthropy Partners member of Baptist Health Foundation for providing support of high quality unbiased continuing medical education at the Immunotherapy Symposium, at which the content for this online activity was recorded.

Bristol-Meyers Squibb

Genentech

Janssen Oncology

 

Additional information
Bibliography: 
  • Mikkilineni, L., & Kochenderfer, J. N. (2017). Chimeric antigen receptor T-cell therapies for multiple myeloma. Blood, The Journal of the American Society of Hematology, 130(24), 2594-2602.
  • Sackstein, R. (2016). Fulfilling Koch's postulates in glycoscience: HCELL, GPS and translational glycobiology. Glycobiology, 26(6), 560-570.
  • Dimitroff, C. J., Lee, J. Y., Rafii, S., Fuhlbrigge, R. C., & Sackstein, R. (2001). CD44 is a major E-selectin ligand on human hematopoietic progenitor cells. The Journal of cell biology, 153(6), 1277-1286.

Related Topics

Miami Cancer Institute Online Series (Multiple Modules)
This online educational series features Miami Cancer Institute (MCI) physician experts and national subject matter experts who have presented at our recent symposiums. Topics highlight the latest advances in cancer imaging, chemotherapy, surgical interventions, radiotherapy and proton therapy. Visit us often, as this catalog will be updated frequently.
Course Summary
Available credit: 
  • 1.00 AMA PRA Category 1 Credit™
  • 1.00 General certificate of attendance
  • 1.00 Nurse Practitioners
  • 1.00 Florida Board of Nursing
  • 1.00 Florida Board of Pharmacy
Course opens: 
06/01/2020
Course expires: 
09/30/2022

Robert Sackstein, M.D.
Interim Chair, Department of Translational Medicine
Dean and Senior Vice President for Health Affairs, and Professor
Florida International University
Miami, Florida

Robert Sackstein, M.D., faculty for this educational activity, has indicated that he is a consultant with Biotechne/R&D Systems and Mesoblast Ltd., and he has licenses with Warrior Therapeutics LLC, Mesoblast Ltd., and Biotechne/R&D Systems. He also has equity with Warrior Therapeutics, LLC. He will not include off-label or unapproved product usage in his presentation or discussion.

All of the relevant financial relationships listed for this individual has been mitigated.

This online course is a highlight from the Inaugural Miami Cancer Institute Immunotherapies Summit.

Guenther Koehne, M.D., Ph.D.
Deputy Director of Miami Cancer Institute
Chief of Blood & Marrow Transplant and Hematologic Oncology
Miami Cancer Institute 
Miami, Florida

Guenther Koehne, M.D., Ph.D., conference director for this educational activity, has no relevant financial relationship with ineligible companies* to disclose. 

Non-faculty contributors and others involved in the planning, development, and editing/review of the content have no relevant financial relationships to disclose with ineligible companies*. 

*Ineligible companies -- Companies whose primary business is producing, marketing, selling, re-selling, or distributing healthcare products used by or on patients.

Disclosure Policy and Disclaimer

Baptist Health South Florida is accredited by the Accreditation Council for Continuing Medical Education (ACCME) to provide continuing medical education for physicians. Baptist Health has been re-surveyed by the ACCME and awarded Commendation for 6 years as a provider of CME for physicians.
              
Baptist Health South Florida designates this enduring material for a maximum of 1 AMA PRA Category 1 Credits™. Physicians should claim only the credit commensurate with the extent of their participation in the activity.

Available Credit

  • 1.00 AMA PRA Category 1 Credit™
  • 1.00 General certificate of attendance
  • 1.00 Nurse Practitioners
  • 1.00 Florida Board of Nursing
  • 1.00 Florida Board of Pharmacy
Please login or register for a Baptist Health CME account to take this course.

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