GLP-1 Receptor Antagonism: A New Frontier in Cardiovascular Health

Cardiovascular diseases are still among the leading causes of mortality and morbidity in the world. To address this critical issue, the past decade has witnessed a surge in cardiovascular outcome trials focused on evaluating the cardiovascular safety and efficacy of various drugs. One class of drugs that has gained significant attention is the glucagon-like peptide-1 receptor agonists (GLP-1 RA). 

In this online course, Dr. Herbert D. Aronow will discuss the novel cardiovascular applications of GLP-1 RA drugs in the assessment and treatment of cardiovascular diseases.

This course is part of the Jose “Pepe” Alvarez Jr., M.D., Memorial Lecture.

About Dr. José A. “Pepe” Alvarez, Jr.

José A. “Pepe” Alvarez, Jr., M.D.,  a longtime clinical leader of Miami Cardiac & Vascular Institute and its distinguished medical director of vascular surgery, died of brain cancer in 2006 at the age of 53.  Dr. Alvarez, who was also chief of vascular surgery at Baptist Hospital of Miami, was the first Board-certified vascular surgeon in South Florida and essentially pioneered the development of his specialty in this community. He was an integral part of the development of Miami Cardiac & Vascular Institute, a respected colleague and cherished friend.

As a tribute to the professional achievements and the memory of Dr. Alvarez, an endowment has been established for the annual José A. "Pepe" Alvarez, Jr., M.D., Memorial Lecture on Vascular Disease. 

For 20 years, Dr. Alvarez practiced general and vascular surgery at Cedars Hospital and Baptist Hospital of Miami as a member of the Surgical Group of Miami. An active member of the American Board of Surgery with special qualifications in vascular surgery, Dr. Alvarez was past president of both the South Florida Vascular Society and the Florida Society of Vascular Surgery. He was an active member in the Southern Association for Vascular Surgery.

Target Audience

Cardiologists, Vascular Surgeons, Interventional Radiologists, Interventional Cardiologists, Primary Care Physicians, Podiatrists, Emergency Medicine Physicians, General Internists, Advance Practice Registered Nurses, Family Medicine Physicians, Internal Medicine Physicians, Endocrinologists, Nurses and other interested healthcare providers.

Learning Objectives

  • Evaluate GLP-1 RA mediated cardiovascular risk factor modification.
  • Assess reduction in atherothrombotic event risk through GLP-1 RA.
  • Explore potential novel cardiovascular applications for GLP-1 RA.
Additional information
Bibliography: 
  • Marx, N., Husain, M., Lehrke, M., Verma, S., & Sattar, N. (2022). GLP-1 receptor agonists for the reduction of atherosclerotic cardiovascular risk in patients with type 2 diabetes. Circulation, 146(24), 1882-1894.
  • Myasoedova, V. A., Bozzi, M., Valerio, V., Moschetta, D., Massaiu, I., Rusconi, V., ... & Poggio, P. (2023). Anti-Inflammation and Anti-Oxidation: The Key to Unlocking the Cardiovascular Potential of SGLT2 Inhibitors and GLP1 Receptor Agonists. Antioxidants, 13(1), 16.
  • Piccini, S., Favacchio, G., Panico, C., Morenghi, E., Folli, F., Mazziotti, G., ... & Mirani, M. (2023). Time-dependent effect of GLP-1 receptor agonists on cardiovascular benefits: a real-world study. Cardiovascular Diabetology, 22(1), 69.
Course Summary
Available credit: 
  • 1.00 AMA PRA Category 1 Credit™
  • 1.00 General certificate of attendance
  • 1.00 Nurse Practitioners
  • 1.00 Florida Board of Nursing
  • 1.00 Florida Board of Podiatric Medicine
Course opens: 
08/01/2024
Course expires: 
07/31/2027

Herbert D. Aronow, M.D., MPH, FACC, FSCAI, FSVM
Past President, Society for Vascular Medicine
Professor of Medicine, Michigan State University College of Human Medicine
Medical Director, Heart & Vascular Services
Benson Ford Chair in Heart & Vascular
Henry Ford Health
Detroit, Michigan

Herbert D. Aronow, M.D., MPH, faculty for this educational activity, is a consultant for Philips, ReCor Medical and Silk Road Medical, and has indicated that the presentation or discussion will include off-label or unapproved product usage.

Barry T. Katzen, M.D., conference director for this activity, is a consultant for Philips, Gore and Boston Scientific. 

All of the relevant financial relationships listed for these individuals have been mitigated.

Non-faculty contributors and others involved in the planning, development, and editing/review of the content have no relevant financial relationships to disclose with ineligible companies*.

*Ineligible companies - Companies whose primary business is producing, marketing, selling, re-selling, or distributing healthcare products used by or on patients.  

Baptist Health South Florida is accredited by the Accreditation Council for Continuing Medical Education (ACCME) to provide continuing medical education for physicians. Baptist Health has been re-surveyed by the ACCME and awarded Commendation for 6 years as a provider of CME for physicians.
              
Baptist Health South Florida designates this enduring material for a maximum of 1 AMA PRA Category 1 Credits™. Physicians should claim only the credit commensurate with the extent of their participation in the activity.

Available Credit

  • 1.00 AMA PRA Category 1 Credit™
  • 1.00 General certificate of attendance
  • 1.00 Nurse Practitioners
  • 1.00 Florida Board of Nursing
  • 1.00 Florida Board of Podiatric Medicine
Please login or register for a Baptist Health CME account to take this course.

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