Management of High-Risk Breast Cancer Patients

In the United States, 1 in 8 women (12%) will develop invasive breast cancer. Risk assessment is paramount to individualize screening and risk-reducing strategies. Review breast cancer risk factors and surveillance strategies with Melissa L. Pilewskie, M.D., from Memorial Sloan Kettering Cancer Center. 

Target Audience

Breast Surgeons, General Surgeons, Reconstructive Surgeons, Obstetricians and Gynecologists, Oncologists, Medical Oncologists, Physiatrists, Radiation Oncologists, General Practitioners and all other interested healthcare professionals.

Learning Objectives

  • Recognize breast cancer risk factors.
  • Implement strategies for surveillance and risk reduction among high-risk women.
  • Explain ongoing efforts to identify nontoxic risk-reducing options.
Additional information
  • Kuchenbaecker, K. B., Hopper, J. L., Barnes, D. R., Phillips, K. A., Mooij, T. M., Roos-Blom, M. J., ... & Goldgar, D. E. (2017). Risks of breast, ovarian, and contralateral breast cancer for BRCA1 and BRCA2 mutation carriers. Jama, 317(23), 2402-2416.
  • Moskowitz, C. S., Chou, J. F., Wolden, S. L., Bernstein, J. L., Malhotra, J., Friedman, D. N., ... & Smith, S. A. (2014). Breast cancer after chest radiation therapy for childhood cancer. Journal of Clinical oncology, 32(21), 2217.
  • Boughey, J. C., Hartmann, L. C., Anderson, S. S., Degnim, A. C., Vierkant, R. A., Reynolds, C. A., ... & Pankratz, V. S. (2010). Evaluation of the Tyrer-Cuzick (International Breast Cancer Intervention Study) model for breast cancer risk prediction in women with atypical hyperplasia. Journal of Clinical Oncology, 28(22), 3591.
Course Summary
Available credit: 
  • 0.50 AMA PRA Category 1 Credit™
  • 0.50 General certificate of attendance
Course opens: 
Course expires: 

Melissa L. Pilewskie, M.D.
Assistant Attending
Breast Service, Department of Surgery
Memorial Sloan Kettering Cancer Center

Melissa L. Pilewskie, M.D., faculty for this educational activity, has no relevant financial relationship with ineligible companies* to disclose and has indicated that the presentation or discussion will not include off-label or unapproved product usage. 

Symposium Directors

Gladys L. Giron, M.D., has indicated that her spouse is a member of the speakers' bureau and a consultant with Stryker.

John P. Diaz, M.D., has indicated that he is a member of the speakers' bureau with AstraZeneca and consultant with ConMed and Intuitive Surgical.

Nicholas C. Lambrou, M.D., has no relevant financial relationship with ineligible companies* to disclose.

Starr K. Mautner, M.D., has no relevant financial relationship with ineligible companies* to disclose.

All of the relevant financial relationships listed for these individuals have been mitigated.

Non-faculty contributors and others involved in the planning, development, and editing/review of the content have no relevant financial relationships to disclose with ineligible companies*.  

*Ineligible companies -- Companies whose primary business is producing, marketing, selling, re-selling, or distributing healthcare products used by or on patients.

Disclosure Policy and Disclaimer

Baptist Health South Florida is accredited by the Accreditation Council for Continuing Medical Education (ACCME) to provide continuing medical education for physicians. Baptist Health has been re-surveyed by the ACCME and awarded Commendation for 6 years as a provider of CME for physicians.
Baptist Health South Florida designates this enduring material for a maximum of 0.5 AMA PRA Category 1 Credits™. Physicians should claim only the credit commensurate with the extent of their participation in the activity.

Available Credit

  • 0.50 AMA PRA Category 1 Credit™
  • 0.50 General certificate of attendance
Please login or register for a Baptist Health CME account to take this course.

Required Hardware/Software

PC/Mac Users
PC/Mac Users

This site is supported on the most recent stable releases of the following browsers:

Click Here to Download Google Chrome
Google Chrome
Microsoft Edge
Microsoft Edge
Moxilla Firefox
Mozilla Firefox
Internet Explorer

Attention: Internet Explorer Users
This site offers limited support for Internet Explorer 11 (IE11). When using IE11, you will be prompted to download course videos instead of viewing them in the browser. After the course video downloads, the recordings will play.

Mobile Users
Mobile Users

This site is supported on the following mobile devices:

  • Apple iOS mobile devices running iOS 10 or later
  • Android mobile devices running Android 4.4 or later, with the latest release of Google Chrome or Mozilla Firefox
Technical Support
Technical Support

If you are experiencing technical difficulties or have received an error message, please send an email to and include a print screen of the error message, your browser name and version, username and URL where the error occurred. You can expect a response within 48 hours.