Adjuvant Radiation in Endometrial Cancer

In this course, William Small, M.D., discusses roles and techniques in the use of radiation for early-stage and advanced-stage endometrial cancer, including references to several clinical trials and new directions in treatment.

Commercial Supporter

Baptist Health gratefully acknowledges the commercial support provided by Varian for the Women’s Cancers Online Curriculum.

Target Audience

Radiation Oncologists, Medical Oncologists, Surgical Oncologists, Radiologists, Advanced Practice Registered Nurses, Physician Assistants/Physician Associates, and Nurses.

Learning Objectives

  • Identify the patterns of recurrence for endometrial cancer.
  • Explain the techniques of radiation for early-stage endometrial cancer.
  • Implement new developments of molecular-driven therapy.
Additional information

León-Castillo, A., de Boer, S. M., Powell, M. E., Mileshkin, L. R., Mackay, H. J., Leary, A., Nijman, H. W., Singh, N., Pollock, P. M., Bessette, P., Fyles, A., Haie-Meder, C., Smit, V. T. H. B. M., Edmondson, R. J., Putter, H., Kitchener, H. C., Crosbie, E. J., de Bruyn, M., Nout, R. A., Horeweg, N., … TransPORTEC consortium (2020). Molecular Classification of the PORTEC-3 Trial for High-Risk Endometrial Cancer: Impact on Prognosis and Benefit From Adjuvant Therapy. Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 38(29), 3388–3397. 

Small, W., Jr, Bosch, W. R., Harkenrider, M. M., Strauss, J. B., Abu-Rustum, N., Albuquerque, K. V., Beriwal, S., Creutzberg, C. L., Eifel, P. J., Erickson, B. A., Fyles, A. W., Hentz, C. L., Jhingran, A., Klopp, A. H., Kunos, C. A., Mell, L. K., Portelance, L., Powell, M. E., Viswanathan, A. N., Yacoub, J. H., … Gaffney, D. K. (2021). NRG Oncology/RTOG Consensus Guidelines for Delineation of Clinical Target Volume for Intensity Modulated Pelvic Radiation Therapy in Postoperative Treatment of Endometrial and Cervical Cancer: An Update. International journal of radiation oncology, biology, physics, 109(2), 413–424. 

Klopp, A. H., Yeung, A. R., Deshmukh, S., Gil, K. M., Wenzel, L., Westin, S. N., Gifford, K., Gaffney, D. K., Small, W., Jr, Thompson, S., Doncals, D. E., Cantuaria, G. H. C., Yaremko, B. P., Chang, A., Kundapur, V., Mohan, D. S., Haas, M. L., Kim, Y. B., Ferguson, C. L., Pugh, S. L., … Bruner, D. W. (2018, November 28 – 2022, May 20). A Randomized Phase III Study Of Standard Vs. IMRT Pelvic Radiation For Post-Operative Treatment Of Endometrial And Cervical Cancer (TIME-C)--RTOG CCOP Study. Identifier: NCT01672892. 

Course Summary
Available credit: 
  • 1.25 AMA PRA Category 1 Credit™
  • 1.25 General certificate of attendance
  • 1.00 Nurse Practitioners
  • 1.00 Florida Board of Nursing
Course opens: 
Course expires: 

William Small, M.D., FACRO, FACR, FASTRO
Professor and Chairman, Department of Radiation Oncology
Director, Cardinal Bernardin Cancer Center
Stritch School of Medicine
Loyola University Chicago
Chicago, Illinois

William Small, M.D., faculty for this educational activity, is an advisor and member of the data monitoring committee for Novocure, a speaker for Carl Zeiss Medical. He has indicated that the presentation or discussion will not include off-label or unapproved product usage.

Michael Chuong, M.D., conference director for this educational activity, is a researcher with ViewRay, Novocure and AstraZeneca; a consultant with ViewRay; an advisor with ViewRay and Advanced Accelerator Applications; is a member of the speakers' bureau for ViewRay, Elekta and Sirtex. All of the relevant financial relationships listed for this individual have been mitigated.

Non-faculty contributors and others involved in the planning, development, and editing/review of the content have no relevant financial relationships to disclose with ineligible companies*

*Ineligible companies - Companies whose primary business is producing, marketing, selling, re-selling, or distributing healthcare products used by or on patients.

Baptist Health South Florida is accredited by the Accreditation Council for Continuing Medical Education (ACCME) to provide continuing medical education for physicians. Baptist Health has been re-surveyed by the ACCME and awarded Commendation for 6 years as a provider of CME for physicians.
Baptist Health South Florida designates this enduring material for a maximum of 1.25 AMA PRA Category 1 Credits™. Physicians should claim only the credit commensurate with the extent of their participation in the activity.

Available Credit

  • 1.25 AMA PRA Category 1 Credit™
  • 1.25 General certificate of attendance
  • 1.00 Nurse Practitioners
  • 1.00 Florida Board of Nursing
Please login or register for a Baptist Health CME account to take this course.

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