Thrombophilia Testing: Are we wasting cash and blood?

Management of venous thromboembolism (VTE) includes evaluation for hypercoagulable states, particularly when VTE occurs in younger patients, is persistent or is linked with family history. Laboratory tests are costly and evidence is limited in terms of better patient outcomes. Evidence based on observational prospective studies suggests that optimal duration of anticoagulation should be based on clinical risks resulting in VTE, such as transient, permanent and idiopathic or unprovoked risks, and less on abnormal thrombophilia values. This course will address patient screening and selection as well as factors for determinng when testing is indicated to assess thrombophilia.

Target Audience

Internists, Emergency Medicine Physicians, Cardiologists, Hematologists/Oncologists, Pulmonary/Critical Care Physicians, Interventional Radiologists, General Surgeons, Vascular Surgeons, Physician Assistants and all physicians who treat patients with chest pain, hypertension, atherosclerosis and deep-vein thrombosis. 

Learning Objectives

  • Critically analyze the clinical interpretations of thrombophilia tests.
  • Determine which patient type specific results influence when managing venous thromboembolism. 
Additional information
Bibliography: 

Masuda, EM, Lee, RW, Okazaki, IJ, Benyamini, P, Kistner, RL, (2015). Venous and lymphatic Disorders. Journal of Vascular Surgery: 3(2): 228-235.

Course summary
Available credit: 
  • 0.50 AMA PRA Category 1 Credit™
  • 0.50 General certificate of attendance
Course opens: 
05/01/2016
Course expires: 
05/01/2018

Steven Fein, M.D. 
Hematologist/Oncologist
Baptist, South Miami, Doctors, Homestead, Mariners and West Kendall Baptist Hospitals
Voluntary Assistant Professor of Medicine, University of Miami Miller School of Medicine
Miami, Florida

Steven Fein, M.D., has indicated that he has consulted for Boeringer Ingelheim, Janssen, BMS and Pfizer. Dr. Fein has also indicated that his discussions will not include mention of investigational or off-label usage.

Non-faculty contributors and others involved in the planning, development and editing/review of the content have no relevant financial relationships to disclose.

Disclosure Policy and Disclaimer

Baptist Health South Florida is accredited by the Accreditation Council for Continuing Medical Education (ACCME) to provide continuing medical education for physicians. Baptist Health has been re-surveyed by the ACCME and awarded Commendation for 6 years as a provider of CME for physicians.
             
Baptist Health South Florida designates this enduring material for a maximum of 0.50 AMA PRA Category 1 Credit™. Physicians should claim only the credit commensurate with the extent of their participation in the activity.

Available Credit

  • 0.50 AMA PRA Category 1 Credit™
  • 0.50 General certificate of attendance

Accreditation Period

Course opens: 
05/01/2016
Course expires: 
05/01/2018
Please login or register to take this course.

Required Hardware/software

This site is best viewed on the two most recent stable releases of the following browsers for all public pages:

PCs Running Windows

  • Google Chrome (Preferred): Download free web browser for PC, Mac, phone and tablet
  • Internet Explorer (IE 11 and above recommended): You will be prompted to download videos before you are able to view. Click “download” to view video.  After a momentary pause, the recording will play. 
  • Mozilla Firefox: You may be prompted under the “This Connection is Untrusted” screen to add “cmeonline.baptisthealth.net” and “cdn.baptisthealth.net” under “add exceptions”.

Apple Computers Running OSX

  • Google Chrome (Preferred): Download free web browser for PC, Mac, phone and tablet
  • Safari
  • Mozilla Firefox: You may be prompted under the “This Connection is Untrusted” screen to add “cmeonline.baptisthealth.net” and “cdn.baptisthealth.net” under “add exceptions”.

This site uses a responsive design, which allows the page layout of elements to change depending on the screen resolution. Certain functionality may change based on the screen resolution of smaller screens, such as the number of columns in a table.

Technical Support: If you are experiencing technical difficulties or have received an error message, please send an email to CME@BaptistHealth.net and include a print screen of the error message, your browser name and version, username and URL where the error occurred. You can expect a response within 48 hours.