A Fluoroquinolone Story: 1960s to 2020s

Fluoroquinolones are widely used in clinical practice. These antimicrobials come with multiple safety concerns. This course will review scenarios in which fluoroquinolones may be considered the drug of choice and when alternative medications should be considered the primary intervention.  

Target Audience

Physicians, physician assistants, advanced practice registered nurses, nurses, pharmacists, pharmacy technicians and other interested healthcare professionals.

Learning Objectives

  • Explain the history of fluoroquinolones in clinical practice and delineate safety concerns related to these antimicrobials.
  • Utilize the Food and Drug Administration guidelines on the appropriate use of fluoroquinolones in clinical practice.
  • Counsel patients regarding the potential unintended consequences of fluoroquinolones.
  • Document reason for fluoroquinolones accurately in the medical record when other alternatives have been exhausted.
Additional information
Bibliography: 
  • Sellick, J., Mergenhagen, K., Morris, L., Feuz, L., Horey, A., Risbood, V., ... & Ott, M. (2018). Fluoroquinolone-related neuropsychiatric events in hospitalized veterans. Psychosomatics, 59(3), 259-266.
  • Labay-Kamara, U., Manning, S., & McMahon, T. (2012). Fluoroquinolone–Induced Suicidal Ideation and Suicidality. Psychosomatics, 1(53), 97-98.
  • Appelbaum, P. C., & Hunter, P. A. (2000). The fluoroquinolone antibacterials: past, present and future perspectives. International journal of antimicrobial agents, 16(1), 5-15.
Course summary
Available credit: 
  • 1.00 ABIM MOC
  • 1.00 AMA PRA Category 1 Credit™
  • 1.00 General certificate of attendance
  • 1.00 Nurse Practitioners
  • 1.00 Florida Board of Nursing
  • 1.00 Florida Board of Pharmacy
Course opens: 
02/01/2020
Course expires: 
01/31/2023

Timothy P. Gauthier, Pharm.D., BCPS-AQ ID
Antimicrobial Stewardship Clinical Program Manager
Baptist Health South Florida

Stacey Baker, M.D.
Infectious Diseases Specialist
Baptist, South Miami, Doctors Hospitals

Antimicrobial Stewardship Continuing Education Subcommittee
Stacey Baker, M.D.
Infectious Diseases Specialist
Baptist, South Miami, Doctors Hospitals

Richard Levine, M.D. 
Infectious Diseases Specialist
Baptist, South Miami, Doctors Hospitals

Jorge Murillo, M.D.
Infectious Diseases Specialist
Baptist, South Miami, Doctors Hospitals

Stacey Baker, M.D., and Timothy P. Gauthier, Pharm.D., BCPS-AQ ID, have indicated that neither they nor their spouses/partners have relevant financial relationships with commercial interest companies, and they will not include off-label or unapproved product usage in their presentation(s) or discussion(s).

Richard Levine, M.D., has indicated that neither he nor his spouse/partner has relevant financial relationships with commercial interest companies.

Jorge Murillo, M.D., subcommittee member, is on the speakers bureau for Merck.

All other non-faculty contributors, subcommittee members, content reviewers and others involved in the planning, development and editing/review of the content have no relevant financial relationships to disclose.

Disclosure Policy and Disclaimer

Baptist Health South Florida is accredited by the Accreditation Council for Continuing Medical Education (ACCME) to provide continuing medical education for physicians. Baptist Health has been re-surveyed by the ACCME and awarded Commendation for 6 years as a provider of CME for physicians.
              
Baptist Health South Florida designates this enduring material for a maximum of 1 AMA PRA Category 1 Credits™. Physicians should claim only the credit commensurate with the extent of their participation in the activity.

American Board of Internal Medicine Maintenance of Certification<

Successful completion of this CME activity, which includes participation in the evaluation component, enables the participant to earn up to 1 Medical Knowledge MOC points in the American Board of Internal Medicine's (ABIM) Maintenance of Certification (MOC) program. Participants will earn MOC points equivalent to the amount of CME credits claimed for the activity. It is the CME activity provider's responsibility to submit participant completion information to ACCME for the purpose of granting ABIM MOC credit.

Your participation information will be shared with the ACCME, which will in turn report your points to ABIM. Successful completion of a course examination is required to earn ABIM MOC points.

NOTE: Maintenance of Certification (MOC) points will be automatically reported to the ABIM. Submissions are recorded in approximately 48 hours. You will receive an email when your credits have been processed.

Through an agreement between the Accreditation Council for Continuing Medical Education and the Royal College of Physicians and Surgeons of Canada, medical practitioners participating in the Royal College MOC Program may record completion of accredited activities registered under the ACCME’s “CME in Support of MOC” program in Section 3 of the Royal College’s MOC Program.

 

Available Credit

  • 1.00 ABIM MOC
  • 1.00 AMA PRA Category 1 Credit™
  • 1.00 General certificate of attendance
  • 1.00 Nurse Practitioners
  • 1.00 Florida Board of Nursing
  • 1.00 Florida Board of Pharmacy
Please login or register to take this course.

Required Hardware/software

PC/Mac Users
PC/Mac Users

This site is supported on the most recent stable releases of the following browsers:

Click Here to Download Google Chrome
Google Chrome
Microsoft Edge
Microsoft Edge
Safari
Safari
Moxilla Firefox
Mozilla Firefox
Internet Explorer

Attention: Internet Explorer Users
This site offers limited support for Internet Explorer 11 (IE11). When using IE11, you will be prompted to download course videos instead of viewing them in the browser. After the course video downloads, the recordings will play.

Mobile Users
Mobile Users

This site is supported on the following mobile devices:

  • Apple iOS mobile devices running iOS 10 or later
  • Android mobile devices running Android 4.4 or later, with the latest release of Google Chrome or Mozilla Firefox
Technical Support
Technical Support

If you are experiencing technical difficulties or have received an error message, please send an email to CME@baptisthealth.net and include a print screen of the error message, your browser name and version, username and URL where the error occurred. You can expect a response within 48 hours.