Familial Hypercholesterolemia: Clinical Update

Familial hypercholesterolemia is associated with a high risk for premature coronary artery disease. Health professionals should be alert to the signs found during a physical examination and to the laboratory values suggestive of familial hypercholesterolemia in order to help prevent or slow the progression of coronary atherosclerosis.

Target Audience

Cardiologists, Endocrinologists, Family Physicians, General Internists, Gynecologists, Internal Medicine Physicians, Physician Assistants and Fellows. 

Learning Objective

  • Detect and properly manage familial hypercholesterolemia to prevent or slow progression of coronary atherosclerosis.
Additional information
Bibliography: 
  • Goldstein, Joseph L. "Familial hypercholesterolemia." (2001). http://emedicine.medscape.com/article/121298-overview  
  • Lambert, G., Charlton, F., Rye, K. A., & Piper, D. E. (2009). Molecular basis of PCSK9 function. Atherosclerosis, 203(1), 1-7.
  • Austin, M. A., Hutter, C. M., Zimmern, R. L., & Humphries, S. E. (2004). Genetic causes of monogenic heterozygous familial hypercholesterolemia: a HuGE prevalence review. American journal of epidemiology, 160(5), 407-420.
  • Varret, M., Abifadel, M., Rabès, J. P., & Boileau, C. (2008). Genetic heterogeneity of autosomal dominant hypercholesterolemia. Clinical genetics, 73(1), 1-13.
  • Soutar, A. K., & Naoumova, R. P. (2007). Mechanisms of disease: genetic causes of familial hypercholesterolemia. Nature clinical practice Cardiovascular medicine, 4(4), 214-225.
Course summary
Available credit: 
  • 0.75 AMA PRA Category 1 Credit™
  • 0.75 ABIM MOC
  • 0.75 General certificate of attendance
Course opens: 
05/01/2017
Course expires: 
05/01/2019
Rating: 
0

Paul E. Ziajka, M.D., Ph.D., FNLA     
Cardiologist, Private Practice
Assistant Professor, Internal Medicine
University of Central Florida College of Medicine
Clinical Assistant Professor, Department of Clinical Sciences
Florida State University School of Medicine
Orlando, Florida

Paul E. Ziajka, M.D., Ph.D., FNLA, disclosed that he receives grant/research support from Amgen, Regeneron and Sanofi; also, he is a member of the speakers bureau for Amgen, Amarin Pharma, Kowa Pharma, Regeneron and Sanofi. Dr. Ziajka has indicated that he will not include off-label or unapproved usage in his presentation or discussion.

Non-faculty contributors and others involved in the planning, development and editing/review of the content have no relevant financial relationships to disclose. 

Disclosure Policy and Disclaimer 

Baptist Health South Florida is accredited by the Accreditation Council for Continuing Medical Education (ACCME) to provide continuing medical education for physicians. Baptist Health has been re-surveyed by the ACCME and awarded Commendation for 6 years as a provider of CME for physicians.
             
Baptist Health South Florida designates this enduring material for a maximum of 0.75 AMA PRA Category 1 Credit™. Physicians should claim only the credit commensurate with the extent of their participation in the activity.

ABIM MOC

Successful completion of this CME activity enables the participant to earn up to 0.75 MOC points in the American Board of Internal Medicine’s (ABIM) Maintenance of Certification (MOC) program. Participants will earn MOC points equivalent to the amount of CME credits claimed for the activity. It is the CME activity provider’s responsibility to submit participant completion information to ACCME for the purpose of granting ABIM MOC points.

Your participation information will be shared with the ACCME, which will in turn report your points to ABIM. Successful completion of a course examination is required to earn ABIM MOC points.

Available Credit

  • 0.75 AMA PRA Category 1 Credit™
  • 0.75 ABIM MOC
  • 0.75 General certificate of attendance

Accreditation Period

Course opens: 
05/01/2017
Course expires: 
05/01/2019
Please login or register to take this course.

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