Physician-Assisted-Suicide (PAS) is one of the most controversial topics in the medical profession. PAS occurs when a physician provides a competent, terminally ill patient with a prescription for a lethal dose of medication, upon the patient’s request, with the intent for the patient to end his/her own life. The American public and the medical profession both remain deeply divided on the question of whether to legalize PAS. PAS is legally acceptable by state law in Oregon, Washington, Colorado, Vermont, California and the District of Columbia, and by court ruling in Montana. In this policy debate Dr. Barry Kinzbrunner will discuss the religious underpinnings, historical precedents and the late 20th and early 21st century experiences in support of his opposition to PAS, while Dr. Fleur Sack will discuss the principle arguments in support PAS, such as patient autonomy, mercy and nonabandonment.