Fructose and Metabolic Syndrome: Is There a Link?

What is the connection between sugar, obesity and cardiovascular disease? Learn from Dr. Robert Lustig about insulin resistance, insulin hypersecretion and the next nutritional war.

Target Audience

Cardiologists, Family Physicians, General Internists, Endocrinologists, Gynecologists, Nurses, Nursing Practitioners and Physician Assistants.

LEARNING OBJECTIVES

  • Recognize the effects of insulin on the liver and the pathogenesis of hepatic insulin resistance.
  • Differentiate between hepatic glucose vs. fructose metabolism.
  • Describe the reasons for, and magnitude of, fructose addition to processed food. 
Additional information
Bibliography: 
  • The prevalence of the metabolic syndrome is high among obese children and adolescents, and it increases with worsening obesity. Biomarkers of an increased risk of adverse cardiovascular outcomes are already present in these youngsters. http://www.nejm.org/doi/full/10.1056/NEJMoa031049.
  • Weiss, R., Dziura, J., Burgert, T. S., Tamborlane, W. V., Taksali, S. E., Yeckel, C. W., ... & Sherwin, R. S. (2004). Obesity and the metabolic syndrome in children and adolescents. New England Journal of Medicine, 350(23), 2362-2374.
  • The metabolic syndrome is a clinical condition composed of anthropometric, physiologic and biochemical abnormalities predisposing affected individuals to the development of type 2 diabetes and cardiovascular disease. Rather than total adiposity, the core clinical component of the syndrome is visceral and/or ectopic fat (i.e., fat in organs not designed for fat storage), whereas the principal metabolic abnormality is insulin resistance. http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3289531/.
  • Bremer, A. A., Mietus-Snyder, M., & Lustig, R. H. (2012). Toward a unifying hypothesis of metabolic syndrome. Pediatrics, 129(3), 557-570.
Course Summary
Available credit: 
  • 1.00 AMA PRA Category 1 Credit™
  • 1.00 General certificate of attendance
  • 1.00 Florida Board of Dietitians
  • 1.00 Nurse Practitioners
  • 1.00 Florida Board of Nursing
Course opens: 
04/01/2017
Course expires: 
11/19/2020
Rating: 
0

Robert H. Lustig, M.D. 
Professor of Clinical Pediatrics, Division of Endocrinology
Director, UCSF Weight Assessment for Teen and Child Health (WATCH)
Program
University of California
San Francisco, California

Robert H. Lustig, M.D., indicated that neither he nor his spouse/partner has relevant financial relationships with commercial interest companies, and he will not include off-label or unapproved product usage in his presentations or discussions. 

Non-faculty contributors and others involved in the planning, development and editing/review of the content have no relevant financial relationships to disclose. 

Disclosure Policy and Disclaimer

Baptist Health South Florida is accredited by the Accreditation Council for Continuing Medical Education (ACCME) to provide continuing medical education for physicians. Baptist Health has been re-surveyed by the ACCME and awarded Commendation for 6 years as a provider of CME for physicians.
             
Baptist Health South Florida designates this enduring material for a maximum of 1 AMA PRA Category 1 Credit™. Physicians should claim only the credit commensurate with the extent of their participation in the activity.

Available Credit

  • 1.00 AMA PRA Category 1 Credit™
  • 1.00 General certificate of attendance
  • 1.00 Florida Board of Dietitians
  • 1.00 Nurse Practitioners
  • 1.00 Florida Board of Nursing
Please login or register for a Baptist Health CME account to take this course.

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