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Event Date: Thu, 01/22/2026 - 12:00pm

COURSE DESCRIPTION:
This course provides an in-depth overview of chimeric antigen receptor (CAR) T-cell therapy, focusing on the fundamental biological principles that drive its clinical application. Participants will explore T-cell engineering strategies, antigen targeting, and the mechanisms of immune-mediated cytotoxicity that underpin CAR-T cell function. The course will also examine the evolution of CAR-T therapy from early experimental platforms to currently FDA-approved treatments, as well as emerging next-generation technologies. In addition, learners will identify established clinical indications for CAR-T therapy in hematologic malignancies and review investigational and expanding applications in solid tumors, HIV, and autoimmune diseases.

TARGET AUDIENCE:
Physicians, Baptist Hospital Medical Staff, pharmacists, nurses, and medical residents

LEARNING OBJECTIVES:

• Explain the biological principles underlying CAR-T cell therapy, including T-cell engineering, antigen targeting, and mechanisms of immune-mediated cytotoxicity.
• Describe the evolution of CAR-T therapy from early experimental platforms to FDA-approved treatments and emerging next-generation technologies.
• Identify current clinical indications for CAR-T therapy in hematologic malignancies and recognize investigational applications in solid tumors, HIV, and autoimmune diseases.

FACULTY AND DISCLOSURES:

Marco Ruiz Andia, M.D.
Bone Marrow Transplant
Baptist Health South Florida

Marco Ruiz Andia, M.D., faculty of this educational activity, has no relevant financial relationships with ineligible companies* to disclose, and has indicated that the presentation(s) or discussion(s) will not include off-label or unapproved product usage.

Tina Sanjar, M.D, and Seema Chandra, M.D., Amalia Landa Galindez, directors of this educational activity, have no relevant financial relationships with ineligible companies* to disclose, and have indicated that the presentation(s) or discussion(s) will not include off-label or unapproved product usage.

All of the relevant financial relationships listed for this individual have been mitigated.

Non-faculty contributors and others involved in the planning, development, and editing/review of the content have no relevant financial relationship(s) to disclose with ineligible companies*

*Ineligible companies - Companies whose primary business is producing, marketing, selling, re-selling, or distributing healthcare products used by or on patients.

Disclosure Policy and Disclaimer

ACCREDITATION STATEMENTS AND CREDITS

Baptist Health South Florida is accredited by the Accreditation Council for Continuing Medical Education (ACCME) to provide continuing medical education for physicians. Baptist Health has been re-surveyed by the ACCME and awarded Commendation for 6 years as a provider of CME for physicians.

Baptist Health South Florida designates this live activity for a maximum of 1 AMA PRA Category 1 Credit™.  Physicians should claim only the credit commensurate with the extent of their participation in the activity.   

This activity has been approved for 1 credit hour, CE Broker Course #20-1325054, by the Florida Boards of Medicine, Osteopathic Medicine and Physician Assistants.  

This activity is approved for 1 credit for Nurse Practitioners, Nurses, Dietitians, Pharmacists and Techs and Respiratory Therapists. Baptist Health South Florida CE Broker Provider #50-182.

American Board of Internal Medicine Maintenance of Certification

Successful completion of this CME activity, which includes participation in the evaluation component, enables the participant to earn up to 1 Medical Knowledge MOC points in the American Board of Internal Medicine's (ABIM) Maintenance of Certification (MOC) program. Participants will earn MOC points equivalent to the amount of CME credits claimed for the activity. It is the CME activity provider's responsibility to submit participant completion information to ACCME for the purpose of granting ABIM MOC credit.

Your participation information will be shared with specialty boards through the ACCME's PARS reporting system. Submissions are recorded in approximately 48 hours. You will receive an email when your credits have been processed.