Cancer is a public health problem of major proportions. Each year, more than 600,000 people in the United States die from cancer. There have been many advances in the practice of rehabilitation medicine, psychology, neurology and other clinical specialties that identify and treat patients with cancer. Fatigue and loss of physical performance are frequent problems of cancer patients. This symposium will provide practical, evidence-based strategies to accurately treat oncology patients of various types, including contraindications for treatment.